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Polish scientists co-author first 4D map of human DNA linking genome structure to gene activity

An international team of scientists has published the most comprehensive four-dimensional map of DNA organisation in the human cell nucleus, showing how its spatial arrangement over time influences gene function and can help predict the effects of mutations.

  • Source: Promotion Centre, Faculty of Biology and Environmental Protection, University of Lodz
    Life

    Scientists discover 24 new species of crustaceans in deep Pacific

    Scientists have identified 24 new species of amphipod crustaceans, including an entirely new superfamily, in the depths of the Central Pacific Ocean, one of the least explored ecosystems on Earth.

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    Fish are shrinking due to overfishing and climate change, study warns

    Fish are shrinking not only due to intensive fishing but also because of evolutionary responses to climate change, according to research by scientists from Poland and Australia published in Science.

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    Vegetation in Europe creating ‘climate debt’ by lagging behind climate warming

    Plant communities across Europe are not adapting quickly enough to climate warming, creating a growing “climatic debt” that could drive faster ecological change in the future, according to a study published in Nature.

  • A nest of blue tits with eggs. Credit: Jerzy Bańbura
    Life

    Blue tits use cigarette butts to protect chicks from parasites, study finds

    Blue tits are lining their nests with cigarette butts to reduce parasites and improve the health and survival chances of their chicks, scientists from the University of Lodz have found.

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    Life

    Scientists develop new agent for combating fungal plant diseases

    Scientists at Jagiellonian University have developed a plant-protection preparation based entirely on natural substances that may serve as an effective antifungal agent for crops, with potential use in both large-scale agriculture and organic farming.

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    MicroRNA gene mutations disrupt cellular regulation, study shows

    Polish scientists have identified thousands of mutations in genes encoding microRNA molecules and found that most of them cause the molecules to malfunction, potentially disrupting key biological processes and contributing to disease.

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    Polish scientists uncover key enzyme transport mechanism of dangerous parasite

    Scientists from the Małopolska Centre of Biotechnology at Jagiellonian University have shown that a key enzyme transport system in the parasite Trypanosoma cruzi is more complex than previously believed, providing new insight into a mechanism essential for the organism’s survival.

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    New forensic method combining DNA, fingerprints and biomarkers developed by Polish researchers

    Researchers at the University of Gdańsk have developed a forensic method that combines fingerprint analysis, DNA testing and biomolecule detection, allowing investigators to obtain more information from a single trace.

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    RNA’s structure may explain how life began, Polish scientists find

    RNA’s spatial structure allows it to replicate efficiently without enzymes, a feature that may explain why RNA, not DNA, was the first self-replicating molecule on Earth, according to Polish researchers from the Faculty of Chemistry at Wrocław University of Science and Technology.

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    Polish scientists co-author first 4D map of human DNA linking genome structure to gene activity

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